PUBLICATIONS
Link to Google Scholar
2024
Cancer prevalence across vertebrates
Germline mutation rate predicts cancer mortality across 37 vertebrate species
Life history traits and cancer prevalence in birds
Approaches and methods to study wildlife cancer
Evaluation of Neoplasia, Treatments, and Survival in Lizard Species
Variation in maternal lactation practices associated with changes in diurnal maternal inflammation
Retrospective study of the prevalence, histopathology, therapy, and survival time of neoplastic disease in fish
Sperm intrusion into the implantation-stage blastocyst and its potential biological significance
2023
Is chimerism associated with cancer across the tree of life?
Bridging clinic and wildlife care with AI-powered pan-species computational pathology
2022
Early life adversity, reproductive history, and breast cancer risk
Of elephants and other mammals: A comparative review of reproductive tumors and potential impact on conservation
Cancer susceptibility as a cost of reproduction and contributor to life history evolution
Female Health Across the Tree of Life: Insights at the Intersection of Women's Health, One Health and Planetary Health
Cancer risk across mammals
2021
Elephant genomes reveal accelerated evolution in mechanisms underlying disease defenses
Identifying key questions in the ecology and evolution of cancer
Postpartum depression and mother-offspring conflict over maternal investment
2020
Comparative Oncology: New Insights into an Ancient Disease
Lifetime cancer prevalence and life history traits in mammals
Agent‐based modelling reveals strategies to reduce the fitness and metastatic potential of circulating tumour cell clusters
Molecular biology and evolution of cancer: from discovery to action
Elephant genomes reveal insights into differences in disease defense mechanisms between species
Improving cancer drug discovery by studying cancer across the tree of life
2018
Life history trade-offs in tumors
AM Boddy, W Huang, A Aktipis.
Current pathobiology reports 6 (4), 201-207
Understanding cooperation through fitness interdependence
A Aktipis, L Cronk, J Alcock, JD Ayers, C Baciu, D Balliet, AM Boddy, OS Curry, JA Krems JA, A Muñoz, D Sullivan.
Nature Human Behaviour. 2018 Jul;2(7):429.
2017
Classifying the evolutionary and ecological features of neoplasms
CC Maley, A Aktipis, TA Graham, A Sottoriva, AM Boddy, M Janiszewska, AS Silva, M Gerlinger, Y Yuan, KJ Pienta, KS Anderson, R Gatenby, C Swanton, D Posada, C Wu, JD Schiffman, ES Hwang, K Polyak, ARA Anderson, JS Brown, M Greaves, D Shibata
Nature Reviews Cancer. 2017
Peto’s Paradox: how has evolution solved the problem of cancer prevention?
M Tollis, AM Boddy, CC Maley
BMC biology 15 (1), 60. 2017
Evidence of a Conserved Molecular Response to Selection for Increased Brain Size in Primates
AM Boddy*, PW Harrison*, SH Montgomery*, JA Caravas, MA Raghanti, KA Phillips, NI Mundy, DE Wildman
Genome biology and evolution 9 (3). 2017 | * contributed equally
Evolution of cancer suppression as revealed by mammalian comparative genomics
M Tollis, JD Schiffman, AM Boddy
Current Opinion in Genetics & Development 42, 40-47. 2017
Evolution of Cancer Defense Mechanisms Across Species
VK Harris, JD Schiffman, AM Boddy
Ecology and Evolution of Cancer. Elsevier. 2017
Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks
A Fortunato, AM Boddy, D Mallo, A Aktipis, CC Maley, JW Pepper
Cold Spring Harbor Perspectives in Medicine 7 (2), a029652. 2017
2016
Contextual organismality: Beyond pattern to process in the emergence of organisms
SL Díaz‐Muñoz, AM Boddy, G Dantas, CM Waters, JL Bronstein
Evolution 70 (12), 2669-2677. 2016
When (distant) relatives stay too long: implications for cancer medicine
D Chowell, AM Boddy, D Mallo, M Tollis, CC Maley
Genome biology 17 (1), 34. 2016
Is estrogen receptor negative breast cancer risk associated with a fast life history strategy?
BH Hidaka, AM Boddy
Evolution, medicine, and public health (1), 17-20. 2016
2015
Fetal microchimerism and maternal health: A review and evolutionary analysis of cooperation and conflict beyond the womb
AM Boddy, A Fortunato, M Wilson Sayres, A Aktipis
BioEssays 37 (10), 1106-1118. 2015
Cancer across the tree of life: cooperation and cheating in multicellularity
CA Aktipis, AM Boddy, G Jansen, U Hibner, ME Hochberg, CC Maley, GS Wilkinson
Phil. Trans. R. Soc. B 370 (1673), 20140219. 2015
Cancer susceptibility and reproductive trade-offs: a model of the evolution of cancer defences
AM Boddy, H Kokko, F Breden, GS Wilkinson, CA Aktipis
Phil. Trans. R. Soc. B 370 (1673), 20140220. 2015
2013
Life history tradeoffs in cancer evolution
CA Aktipis, AM Boddy, RA Gatenby, JS Brown, CC Maley
Nature Reviews. Cancer 13 (12), 883. 2013
Characterization of human cortical gene expression in relation to glucose utilization
KN Sterner, MR Mcgowen, HT Chugani, AL Tarca, CC Sherwood, PR Hof, CW Kuzawa, AM Boddy, RL Raaum, A Weckle, L Lipovich, LI Grossman, M Uddin, M Goodman, DE Wildman
American Journal of Human Biology 25 (3), 418-430. 2013
2012
Dynamic gene expression in the human cerebral cortex distinguishes children from adults
KN Sterner, A Weckle, HT Chugani, AL Tarca, CC Sherwood, PR Hof, CW Kuzawa, AM Boddy, A Abbas, RL Raaum, L Grégoire, L Lipovich, LI Grossman, M Uddin, M Goodman, DE Wildman
PloS one 7 (5), e37714. 2012
Comparative analysis of encephalization in mammals reveals relaxed constraints on anthropoid primate and cetacean brain scaling
AM Boddy, MR McGowen, CC Sherwood, LI Grossman, M Goodman, DE Wildman
Journal of evolutionary biology 25 (5), 981-994. 2012
2011
Role of complement cascade in abdominal aortic aneurysms
I Hinterseher, R Erdman, LA Donoso, TR Vrabec, CM Schworer, JH Lillvis, AM Boddy, K Derr, A Golden, WD Bowen, Z Gatalica, N Tapinos, JR Elmore, DP Franklin, JL Gray, RP Garvin, GS Gerhard, DJ Carey, G Tromp, H Kuivaniemi
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1653-1660. 2011
2010
Inhibitory interneurons of the human prefrontal cortex display conserved evolution of the phenotype and related genes
I Hinterseher, R Erdman, LA Donoso, TR Vrabec, CM Schworer, JH Lillvis, AM Boddy, K Derr, A Golden, WD Bowen, Z Gatalica, N Tapinos, JR Elmore, DP Franklin, JL Gray, RP Garvin, GS Gerhard, DJ Carey, G Tromp, H Kuivaniemi
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1653-1660. 2011
Abdominal aortic aneurysms-a complex genetic disease
J Nischan, GM Lenk, AM Boddy, JH Lillvis, G Tromp, H Kuivaniemi
Aneurysms: Types, Risks, Formation and Treatment, Nova Science Publishers. 35-93. 2010
2009
Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12. 3 by genome wide association
JR Elmore, MA Obmann, H Kuivaniemi, G Tromp, GS Gerhard, DP Franklin, AM Boddy, DJ Carey
Journal of Vascular Surgery 49 (6), 1525-1531. 2009
2008
Basic research studies to understand aneurysm disease
AM Boddy, GM Lenk, JH Lillvis, J Nischan, Y Kyo, H Kuivaniemi
Drug News Perspect 21 (3), 142-148. 2008
Abdominal aortic aneurysms are deep, deadly and genetic
H Kuivaniemi, AM Boddy, JH Lillvis, J Nischan, GM Lenk, G Tromp
Aortic aneurysms, new insights into an old problem, 299-323. 2008
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