PUBLICATIONS

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2020

Lifetime cancer prevalence and life history traits in mammals

AM Boddy, LM Abegglen, AP Pessier, JD Schiffman, CC Maley, C Witte
Evolution, Medicine, and Public Health

Postpartum Depression and Mother-offspring Conflict over Maternal Investment

A Gunst, M Sundén, R Korja, A Boddy, J Kotler, EJ Paavonen, …
PsyArXiv

Socioecological conditions shape postpartum immune trajectories

CM Hove, BC Trumble, J Stieglitz, H Kaplan, MD Gurven, AM Boddy, …
AMERICAN JOURNAL OF HUMAN BIOLOGY 32

The role of early life adversity and breast cancer outcomes

AM Boddy, S Rupp, HA Hanson, Z Yu, A Aktipis, KR Smith
AMERICAN JOURNAL OF HUMAN BIOLOGY 32

Agent‐based modelling reveals strategies to reduce the fitness and metastatic potential of circulating tumour cell clusters

M Campenni, AN May, A Boddy, V Harris, AM Nedelcu
Evolutionary Applications

Molecular biology and evolution of cancer: from discovery to action

JA Somarelli, H Gardner, VL Cannataro, EF Gunady, AM Boddy, …
Molecular Biology and Evolution 37 (2), 320-326

Elephant genomes reveal insights into differences in disease defense mechanisms between species

M Tollis, E Ferris, MS Campbell, VK Harris, SM Rupp, TM Harrison, …
BioRxiv

Improving cancer drug discovery by studying cancer across the tree of life

JA Somarelli, AM Boddy, HL Gardner, SB DeWitt, J Tuohy, K Megquier, …
Molecular Biology and Evolution 37 (1), 11-17

2018

Life history trade-offs in tumors

AM Boddy, W Huang, A Aktipis
Current pathobiology reports 6 (4), 201-207

Understanding cooperation through fitness interdependence

A Aktipis, L Cronk, J Alcock, JD Ayers, C Baciu, D Balliet, AM Boddy, OS Curry, JA Krems JA, A Muñoz, D Sullivan.
Nature Human Behaviour. 2018 Jul;2(7):429.

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Cancer across primates: a life history perspective on disease susceptibility

VK Harris, WC Walker, A Zehnder, M Garner, CC Maley, A Boddy
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY 165, 113-114

2017

Classifying the evolutionary and ecological features of neoplasms

CC Maley, A Aktipis, TA Graham, A Sottoriva, AM Boddy, M Janiszewska, AS Silva, M Gerlinger, Y Yuan, KJ Pienta, KS Anderson, R Gatenby, C Swanton, D Posada, C Wu, JD Schiffman, ES Hwang, K Polyak, ARA Anderson, JS Brown, M Greaves, D Shibata
Nature Reviews Cancer. 2017

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Peto’s Paradox: how has evolution solved the problem of cancer prevention?

M Tollis, AM Boddy, CC Maley
BMC biology 15 (1), 60. 2017

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Evidence of a Conserved Molecular Response to Selection for Increased Brain Size in Primates

AM Boddy*, PW Harrison*, SH Montgomery*, JA Caravas, MA Raghanti, KA Phillips, NI Mundy, DE Wildman
Genome biology and evolution 9 (3). 2017 | * contributed equally

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Evolution of cancer suppression as revealed by mammalian comparative genomics

M Tollis, JD Schiffman, AM Boddy
Current Opinion in Genetics & Development 42, 40-47. 2017

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Evolution of Cancer Defense Mechanisms Across Species

VK Harris, JD Schiffman, AM Boddy
Ecology and Evolution of Cancer. Elsevier. 2017

Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks

A Fortunato, AM Boddy, D Mallo, A Aktipis, CC Maley, JW Pepper
Cold Spring Harbor Perspectives in Medicine 7 (2), a029652. 2017

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2016

Contextual organismality: Beyond pattern to process in the emergence of organisms

SL Díaz‐Muñoz, AM Boddy, G Dantas, CM Waters, JL Bronstein
Evolution 70 (12), 2669-2677. 2016

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When (distant) relatives stay too long: implications for cancer medicine

D Chowell, AM Boddy, D Mallo, M Tollis, CC Maley
Genome biology 17 (1), 34. 2016

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Is estrogen receptor negative breast cancer risk associated with a fast life history strategy?

BH Hidaka, AM Boddy
Evolution, medicine, and public health (1), 17-20. 2016

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2015

Fetal microchimerism and maternal health: A review and evolutionary analysis of cooperation and conflict beyond the womb

AM Boddy, A Fortunato, M Wilson Sayres, A Aktipis
BioEssays 37 (10), 1106-1118. 2015

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Cancer across the tree of life: cooperation and cheating in multicellularity

CA Aktipis, AM Boddy, G Jansen, U Hibner, ME Hochberg, CC Maley, GS Wilkinson
Phil. Trans. R. Soc. B 370 (1673), 20140219. 2015

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Cancer susceptibility and reproductive trade-offs: a model of the evolution of cancer defences

AM Boddy, H Kokko, F Breden, GS Wilkinson, CA Aktipis
Phil. Trans. R. Soc. B 370 (1673), 20140220. 2015

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2013

Life history tradeoffs in cancer evolution

CA Aktipis, AM Boddy, RA Gatenby, JS Brown, CC Maley
Nature Reviews. Cancer 13 (12), 883. 2013

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Characterization of human cortical gene expression in relation to glucose utilization

KN Sterner, MR Mcgowen, HT Chugani, AL Tarca, CC Sherwood, PR Hof, CW Kuzawa, AM Boddy, RL Raaum, A Weckle, L Lipovich, LI Grossman, M Uddin, M Goodman, DE Wildman
American Journal of Human Biology 25 (3), 418-430. 2013

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2012

Dynamic gene expression in the human cerebral cortex distinguishes children from adults

KN Sterner, A Weckle, HT Chugani, AL Tarca, CC Sherwood, PR Hof, CW Kuzawa, AM Boddy, A Abbas, RL Raaum, L Grégoire, L Lipovich, LI Grossman, M Uddin, M Goodman, DE Wildman
PloS one 7 (5), e37714. 2012

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Comparative analysis of encephalization in mammals reveals relaxed constraints on anthropoid primate and cetacean brain scaling

AM Boddy, MR McGowen, CC Sherwood, LI Grossman, M Goodman, DE Wildman
Journal of evolutionary biology 25 (5), 981-994. 2012

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2011

Role of complement cascade in abdominal aortic aneurysms

I Hinterseher, R Erdman, LA Donoso, TR Vrabec, CM Schworer, JH Lillvis, AM Boddy, K Derr, A Golden, WD Bowen, Z Gatalica, N Tapinos, JR Elmore, DP Franklin, JL Gray, RP Garvin, GS Gerhard, DJ Carey, G Tromp, H Kuivaniemi
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1653-1660. 2011

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2010

Inhibitory interneurons of the human prefrontal cortex display conserved evolution of the phenotype and related genes

I Hinterseher, R Erdman, LA Donoso, TR Vrabec, CM Schworer, JH Lillvis, AM Boddy, K Derr, A Golden, WD Bowen, Z Gatalica, N Tapinos, JR Elmore, DP Franklin, JL Gray, RP Garvin, GS Gerhard, DJ Carey, G Tromp, H Kuivaniemi
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1653-1660. 2011

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Abdominal aortic aneurysms-a complex genetic disease

J Nischan, GM Lenk, AM Boddy, JH Lillvis, G Tromp, H Kuivaniemi
Aneurysms: Types, Risks, Formation and Treatment, Nova Science Publishers. 35-93. 2010

2009

Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12. 3 by genome wide association

JR Elmore, MA Obmann, H Kuivaniemi, G Tromp, GS Gerhard, DP Franklin, AM Boddy, DJ Carey
Journal of Vascular Surgery 49 (6), 1525-1531. 2009

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2008

Basic research studies to understand aneurysm disease

AM Boddy, GM Lenk, JH Lillvis, J Nischan, Y Kyo, H Kuivaniemi
Drug News Perspect 21 (3), 142-148. 2008

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Abdominal aortic aneurysms are deep, deadly and genetic

H Kuivaniemi, AM Boddy, JH Lillvis, J Nischan, GM Lenk, G Tromp
Aortic aneurysms, new insights into an old problem, 299-323. 2008