PUBLICATIONS

Link to Google Scholar

2024

Cancer prevalence across vertebrates

Compton Z, Harris V, Mellon W, Rupp S, Kapsetaki SE, Wilmot M, Kennington R, Noble K, Baciu C, Ramirez L, Peraza A, Martins B, Sushil S, Aksoy S, Furukawa, Vincze O, Giraudeau M, Duke EG, Spiro S, Flach E, Davidson H, Zehnder A, Graham TA, Troan B, Harrison TM*, Tollis M*, Schiffman JD*, Aktipis A*, Abegglen LM*, Maley CC*, Boddy AM*
Cancer Discovery (2024) *Co-senior authors

Germline mutation rate predicts cancer mortality across 37 vertebrate species

Kapsetaki SE, Compton ZT, Mellon W, Vincze O, Giraudeau MT, Harrison TM, Abegglen LM, Boddy AM, Maley CC, Schiffman JD
EMPH (2024) eoae016

Life history traits and cancer prevalence in birds

Kapsetaki SE, Compton ZT, Dolan J, Harris VK, Mellon W, Rupp SM, Duke EG, Harrison TM, Aksoy S, Giraudeau M, Vincze O, McGraw KJ, Aktipis A, Tollis M, Boddy AM*, Maley CC*
EMPH (2024) 12(1), 105-116. *Co-senior authors

Approaches and methods to study wildlife cancer

Giraudeau M, Vincze O, Dupont S, Seep T, Baines C, Lemaitre JF, Lemberger K, Gentes S, Boddy AM, Dujon AM, Bramwell G, Harris V, Ujvari B, Alix-Panabieres C, Lair S, Sayag D, Conde DA, Colchero F, Harrison TM, Pavard S, Padilla-Morales B, Chevallier D, Hamede R, Roche B, Malkocs T, Aktipis A, Maley C, DeGregori J, Le Loc’h G, Thomas F
J Anim Ecol. (2024) 00:1–19

Evaluation of Neoplasia, Treatments, and Survival in Lizard Species

Willig F, Torpy FJ, Harrison SH, Duke EG, Troan B, Boddy AM, Abegglen LM, Harrison TM
Animals (2024) 7;14(10):1395

Variation in maternal lactation practices associated with changes in diurnal maternal inflammation

Hove CM, Chua KJ, Martin MA, Hubble M, Boddy AM
Scientific Reports (2024) 14(1), 4376

Retrospective study of the prevalence, histopathology, therapy, and survival time of neoplastic disease in fish

Ferraro E, Harrison SH, Duke E, Troan B, Boddy AM, Abegglen LM, Harrison TM
Animals 14.3 (2024): 464

Sperm intrusion into the implantation-stage blastocyst and its potential biological significance

Sengupta, J, Kroneis T, Boddy AM, Roy R, Sarkar A, Sarkar D, Ghosh D, Huppertz B
EMPH. 2024. 12(1), 1-6

2023

Is chimerism associated with cancer across the tree of life?

Kapsetaki SE, Fortunato A, Compton Z, Rupp SM, Nour Z, Riggs-Davis S, Stephenson D, Duke EG, Boddy AM, Harrison T M, Maley CC, Aktipis A
PloS one 18.6 (2023): e0287901

Bridging clinic and wildlife care with AI-powered pan-species computational pathology

AbdulJabbar K, Castillo SP, Hughes K, Davidson H, Boddy AM, Abegglen LM, Murchison EP, Graham TA, Spiro S, Palmieri C, Yuan Y
Nature Communications. 14.1 (2023): 2408

2022

Early life adversity, reproductive history, and breast cancer risk

Boddy AM, Rupp S, Yu Z, Hanson H, Aktipis A, Smith K
Evolution, Medicine and Public Health. 10.1 (2022): 429-438

Of elephants and other mammals: A comparative review of reproductive tumors and potential impact on conservation

Abegglen LM, Harrison TM, Moresco A, Fowles JS, Troan BV, Kiso WK, Schmitt D, Boddy AM, Schiffman JD
Animals. (2022): 12(15), 2005

Cancer susceptibility as a cost of reproduction and contributor to life history evolution

Dujon AM, Boutry J, Tissot S, Lemaitre JF, Boddy AM, Gerard A, Alvergne A, Arnal A, Vincze O, Nicolas D, Giraudeau M, Telonis-Scott M, Schultz A, Pujol P, Biro P, Beckmann C, Hamede R, Roche B, Ujvari B, Thomas F
Frontiers in Ecology and Evolution. 10 (2022): 861103

Cancer risk across mammals

Vincze O, Colchero F, Lemaitre JF, Conde D, Pavard S, Bieuville M, Urrutia AO, Ujvari B, Boddy AM, Maley CC, Thomas F, Giraudeau M
Nature. 601.7892 (2022): 263-267

2021

Elephant genomes reveal accelerated evolution in mechanisms underlying disease defenses

Tollis M, Ferris E, Campbell M, Harris V, Rupp S, Harrison T, Kiso WK, Schmitt D, Aktipis A, Maley C, Boddy AM, Yandell M, Sciffman JD, Abegglen LM
Molecular Biology and Evolution. 38.9 (2021): 3606-3620

Identifying key questions in the ecology and evolution of cancer

Ujvari B, Dujon A, Aktipis A, Alix-Panabières C, Amend S, Boddy AM, Brown J, Capp JP, DeGregori J, Ewald P, Gatenby R, Gerlinger M, Giraudeau M, Hamede R, Hansen E, Kareva I, Maley CC, Marusyk A, McGranahan N, Metzger M, Nedelcu A, Noble R, Nunney L, Pienta K, Polyak K, Pujol P, Read A, Roche B, Sebens S, Solary E, Stanková K, Thomas F, Ewald HS
Evolutionary applications 14.4 (2021): 877-892

Postpartum depression and mother-offspring conflict over maternal investment

Gunst A, Sudén M, Korja R, Boddy AM, Kotler J, Paavonen EJ, Karlsson L, Karlsson H, Antfolk J
Evolution, Medicine and Public Health. 9.1 (2021): 11-23

2020

Comparative Oncology: New Insights into an Ancient Disease

Boddy AM, Harrison T, Abegglen LM
Iscience. (2020): 101373

Lifetime cancer prevalence and life history traits in mammals

AM Boddy, LM Abegglen, AP Pessier, JD Schiffman, CC Maley, C Witte
Evolution, Medicine, and Public Health

Agent‐based modelling reveals strategies to reduce the fitness and metastatic potential of circulating tumour cell clusters

M Campenni, AN May, A Boddy, V Harris, AM Nedelcu
Evolutionary Applications

Molecular biology and evolution of cancer: from discovery to action

JA Somarelli, H Gardner, VL Cannataro, EF Gunady, AM Boddy, …
Molecular Biology and Evolution 37 (2), 320-326

Elephant genomes reveal insights into differences in disease defense mechanisms between species

M Tollis, E Ferris, MS Campbell, VK Harris, SM Rupp, TM Harrison, …
Molecular Biology and Evolution. 38.9 (2021): 3606-3620

Improving cancer drug discovery by studying cancer across the tree of life

JA Somarelli, AM Boddy, HL Gardner, SB DeWitt, J Tuohy, K Megquier, …
Molecular Biology and Evolution 37 (1), 11-17

2018

Life history trade-offs in tumors

AM Boddy, W Huang, A Aktipis.
Current pathobiology reports 6 (4), 201-207

Download PDF

Understanding cooperation through fitness interdependence

A Aktipis, L Cronk, J Alcock, JD Ayers, C Baciu, D Balliet, AM Boddy, OS Curry, JA Krems JA, A Muñoz, D Sullivan.
Nature Human Behaviour. 2018 Jul;2(7):429.

Download PDF

2017

Classifying the evolutionary and ecological features of neoplasms

CC Maley, A Aktipis, TA Graham, A Sottoriva, AM Boddy, M Janiszewska, AS Silva, M Gerlinger, Y Yuan, KJ Pienta, KS Anderson, R Gatenby, C Swanton, D Posada, C Wu, JD Schiffman, ES Hwang, K Polyak, ARA Anderson, JS Brown, M Greaves, D Shibata
Nature Reviews Cancer. 2017

Download PDF

Peto’s Paradox: how has evolution solved the problem of cancer prevention?

M Tollis, AM Boddy, CC Maley
BMC biology 15 (1), 60. 2017

Download PDF

Evidence of a Conserved Molecular Response to Selection for Increased Brain Size in Primates

AM Boddy*, PW Harrison*, SH Montgomery*, JA Caravas, MA Raghanti, KA Phillips, NI Mundy, DE Wildman
Genome biology and evolution 9 (3). 2017 | * contributed equally

Download PDF

Evolution of cancer suppression as revealed by mammalian comparative genomics

M Tollis, JD Schiffman, AM Boddy
Current Opinion in Genetics & Development 42, 40-47. 2017

Download PDF

Evolution of Cancer Defense Mechanisms Across Species

VK Harris, JD Schiffman, AM Boddy
Ecology and Evolution of Cancer. Elsevier. 2017

Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks

A Fortunato, AM Boddy, D Mallo, A Aktipis, CC Maley, JW Pepper
Cold Spring Harbor Perspectives in Medicine 7 (2), a029652. 2017

Download PDF

2016

Contextual organismality: Beyond pattern to process in the emergence of organisms

SL Díaz‐Muñoz, AM Boddy, G Dantas, CM Waters, JL Bronstein
Evolution 70 (12), 2669-2677. 2016

Download PDF

When (distant) relatives stay too long: implications for cancer medicine

D Chowell, AM Boddy, D Mallo, M Tollis, CC Maley
Genome biology 17 (1), 34. 2016

Download PDF

Is estrogen receptor negative breast cancer risk associated with a fast life history strategy?

BH Hidaka, AM Boddy
Evolution, medicine, and public health (1), 17-20. 2016

Download PDF

2015

Fetal microchimerism and maternal health: A review and evolutionary analysis of cooperation and conflict beyond the womb

AM Boddy, A Fortunato, M Wilson Sayres, A Aktipis
BioEssays 37 (10), 1106-1118. 2015

Download PDF

Cancer across the tree of life: cooperation and cheating in multicellularity

CA Aktipis, AM Boddy, G Jansen, U Hibner, ME Hochberg, CC Maley, GS Wilkinson
Phil. Trans. R. Soc. B 370 (1673), 20140219. 2015

Download PDF

Cancer susceptibility and reproductive trade-offs: a model of the evolution of cancer defences

AM Boddy, H Kokko, F Breden, GS Wilkinson, CA Aktipis
Phil. Trans. R. Soc. B 370 (1673), 20140220. 2015

Download PDF

2013

Life history tradeoffs in cancer evolution

CA Aktipis, AM Boddy, RA Gatenby, JS Brown, CC Maley
Nature Reviews. Cancer 13 (12), 883. 2013

Download PDF

Characterization of human cortical gene expression in relation to glucose utilization

KN Sterner, MR Mcgowen, HT Chugani, AL Tarca, CC Sherwood, PR Hof, CW Kuzawa, AM Boddy, RL Raaum, A Weckle, L Lipovich, LI Grossman, M Uddin, M Goodman, DE Wildman
American Journal of Human Biology 25 (3), 418-430. 2013

Download PDF

2012

Dynamic gene expression in the human cerebral cortex distinguishes children from adults

KN Sterner, A Weckle, HT Chugani, AL Tarca, CC Sherwood, PR Hof, CW Kuzawa, AM Boddy, A Abbas, RL Raaum, L Grégoire, L Lipovich, LI Grossman, M Uddin, M Goodman, DE Wildman
PloS one 7 (5), e37714. 2012

Download PDF

Comparative analysis of encephalization in mammals reveals relaxed constraints on anthropoid primate and cetacean brain scaling

AM Boddy, MR McGowen, CC Sherwood, LI Grossman, M Goodman, DE Wildman
Journal of evolutionary biology 25 (5), 981-994. 2012

Download PDF

2011

Role of complement cascade in abdominal aortic aneurysms

I Hinterseher, R Erdman, LA Donoso, TR Vrabec, CM Schworer, JH Lillvis, AM Boddy, K Derr, A Golden, WD Bowen, Z Gatalica, N Tapinos, JR Elmore, DP Franklin, JL Gray, RP Garvin, GS Gerhard, DJ Carey, G Tromp, H Kuivaniemi
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1653-1660. 2011

Download PDF

2010

Inhibitory interneurons of the human prefrontal cortex display conserved evolution of the phenotype and related genes

I Hinterseher, R Erdman, LA Donoso, TR Vrabec, CM Schworer, JH Lillvis, AM Boddy, K Derr, A Golden, WD Bowen, Z Gatalica, N Tapinos, JR Elmore, DP Franklin, JL Gray, RP Garvin, GS Gerhard, DJ Carey, G Tromp, H Kuivaniemi
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1653-1660. 2011

Download PDF

Abdominal aortic aneurysms-a complex genetic disease

J Nischan, GM Lenk, AM Boddy, JH Lillvis, G Tromp, H Kuivaniemi
Aneurysms: Types, Risks, Formation and Treatment, Nova Science Publishers. 35-93. 2010

2009

Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12. 3 by genome wide association

JR Elmore, MA Obmann, H Kuivaniemi, G Tromp, GS Gerhard, DP Franklin, AM Boddy, DJ Carey
Journal of Vascular Surgery 49 (6), 1525-1531. 2009

Download PDF

2008

Basic research studies to understand aneurysm disease

AM Boddy, GM Lenk, JH Lillvis, J Nischan, Y Kyo, H Kuivaniemi
Drug News Perspect 21 (3), 142-148. 2008

Download PDF

Abdominal aortic aneurysms are deep, deadly and genetic

H Kuivaniemi, AM Boddy, JH Lillvis, J Nischan, GM Lenk, G Tromp
Aortic aneurysms, new insights into an old problem, 299-323. 2008